2- (chloromethyl) -5- (trifluoromethyl) -1 3 4-oxadiazole (CAS # 723286-98-4)

Ọrọ Iṣaaju

2- (chloromethyl) -5- (trifluoromethyl) -1,3,4-oxadiazole jẹ agbo-ara ti ara-ara pẹlu agbekalẹ C4H2ClF3N2O.

Iseda:

2- (chloromethyl) -5- (trifluoromethyl) -1,3,4-oxadiazole jẹ ti ko ni awọ si omi alawọ ofeefee tabi ti o lagbara. O ni iduroṣinṣin igbona giga ati inertness kemikali. O jẹ insoluble ninu omi ni iwọn otutu yara, tiotuka ni diẹ ninu awọn olomi Organic gẹgẹbi ethanol ati ether. Agbo naa le jẹ ijuwe nipasẹ awọn ilana bii ariwo oofa iparun ati iwoye pupọ.

Lo:

2- (chloromethyl) -5- (trifluoromethyl) -1,3,4-oxadiazole ni iye ohun elo kan ni aaye kemistri. Nigbagbogbo a lo bi agbedemeji ni iṣelọpọ Organic fun iṣelọpọ ti awọn agbo ogun miiran. Ni afikun, o tun lo bi reagent iwadi ni aaye ti awọn ipakokoropaeku ati oogun.

Ọna Igbaradi:

2- (chloromethyl) -5- (trifluoromethyl) -1,3,4-oxadiazole le ṣepọ nipasẹ awọn ọna oriṣiriṣi. Awọn atẹle jẹ ọna igbaradi ti o wọpọ:

1. Ṣafikun ayase kan (gẹgẹbi triethylamine) si eto apanirun ifaseyin Organic anhydrous.

2. Ṣafikun iye kan ti methyl 3-chloropropionate ati methyl trifluoroformate si eto epo.

3. Aṣeṣe naa ni a ṣe ni iwọn otutu ti o dara labẹ oju-aye inert, ati pe o jẹ dandan lati gbona adalu ifarahan.

4. Sisẹ tabi distillation lati gba ọja naa, lẹhin isọdi ti o yẹ ati gbigbe lati gba ọja mimọ.

Alaye Abo:

2- (chloromethyl) -5- (trifluoromethyl) -1,3,4-oxadiazole jẹ ailewu ni gbogbogbo nigba lilo ati fipamọ daradara. Bibẹẹkọ, bi agbo-ara Organic, o le fa ipalara kan si ilera eniyan ati agbegbe. Ni lilo ati mimu, yẹ ki o tẹle awọn ilana aabo to tọ, ki o yago fun olubasọrọ taara. Awọn ilana aabo ti o yẹ fun agbo yẹ ki o ka ni pẹkipẹki ati tẹle. Ti o ba jẹ dandan, iṣẹ naa yẹ ki o ṣe labẹ itọsọna ti oṣiṣẹ ọjọgbọn.