2- (trifluoromethyl) thiazole-4-carboxylic acid (CAS# 915030-08-9)

Ọrọ Iṣaaju

2- (trifluoromethyl) thiazole-4-carboxylic acid jẹ agbo-ara Organic pẹlu agbekalẹ kemikali C5H2F3NO2S. Iseda rẹ, lilo, agbekalẹ ati alaye ailewu jẹ apejuwe ni isalẹ.

Iseda:

2- (trifluoromethyl) thiazole-4-carboxylic acid jẹ kristali funfun ti o lagbara. O le ti wa ni tituka ni diẹ ninu awọn Organic olomi bi dimethylsulfamide (DMSO) ati erogba disulfide (CS2), sugbon jẹ insoluble ninu omi. Iwọn yo rẹ jẹ nipa 220-223 ° C.

Lo:

2- (trifluoromethyl) thiazole-4-carboxylic acid jẹ agbedemeji iṣelọpọ Organic ti o wọpọ ti a lo. O le ṣee lo lati ṣepọ diẹ ninu awọn agbo ogun bioactive ni aaye oogun, gẹgẹbi awọn oogun ati awọn ipakokoropaeku. Ni afikun, o tun le ṣee lo bi ohun elo aise sintetiki fun awọn awọ ati awọn nkan ti o ni itara.

Ọna:

Igbaradi ti 2- (trifluoromethyl) thiazole-4-carboxylic acid ni a gba ni gbogbogbo nipasẹ iṣesi ti methyl sulfide ati cyanomethane. Awọn igbesẹ kan pato jẹ bi atẹle: akọkọ, 2-amino -1, 3-thiazole ti ṣe atunṣe pẹlu trifluoroacetaldehyde lati ṣe ina 2- (trifluoromethyl) -1, 3-thiazole; lẹhinna, ti o gba 2- (trifluoromethyl) -1, 3-thiazole ti ṣe atunṣe pẹlu cyanomethane lati ṣe agbejade ọja afojusun 2- (trifluoromethyl) thiazole-4-carboxylic acid.

Alaye Abo:

Majele ati ewu ti 2- (trifluoromethyl) thiazole-4-carboxylic acid ko ti ṣe iwadi ni kikun. Bibẹẹkọ, bi kẹmika kan, awọn iṣe aabo gbogbogbo yẹ ki o tẹle, gẹgẹbi wọ awọn ohun elo aabo ti o yẹ (bii awọn gilaasi, awọn ibọwọ ati awọn ẹwu yàrá) ati mimu ni agbegbe ti o ni afẹfẹ daradara. Lẹhin ifihan si agbo-ara yii, agbegbe ti o kan yẹ ki o wa ni mimọ ni kiakia pẹlu ọṣẹ ati omi. Ti o ba jẹ dandan, wa imọran iṣoogun fun iṣakoso siwaju sii.