3-Chloro-5- (trifluoromethyl) pyridine (CAS # 85148-26-1)
| Awọn koodu ewu | R20 / 21/22 - ipalara nipasẹ ifasimu, ni olubasọrọ pẹlu awọ ara ati ti o ba gbe. R36 / 37/38 - Irritating si oju, eto atẹgun ati awọ ara. R25 – Majele ti o ba gbe |
| Apejuwe Abo | S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun. S36 / 37/39 - Wọ aṣọ aabo to dara, awọn ibọwọ ati aabo oju / oju. S36 - Wọ aṣọ aabo to dara. S45 – Ni ọran ti ijamba tabi ti o ba ni ailara, wa imọran iṣoogun lẹsẹkẹsẹ (fi aami han nigbakugba ti o ṣee ṣe.) |
| UN ID | UN 2811 6.1 / PGIII |
| WGK Germany | 3 |
| Akọsilẹ ewu | Irritant |
| Kíláàsì ewu | IRUN, IRUTAN-H |
| Iṣakojọpọ Ẹgbẹ | III |
Ọrọ Iṣaaju
3-choro-5- (trifluoromethyl) pyridine jẹ agbo alumọni kan pẹlu agbekalẹ kemikali C≡H₂ ClFΛ N. Ko ni awọ si omi alawọ ofeefee kan pẹlu õrùn õrùn kan. Awọn atẹle jẹ apejuwe ti iseda, lilo, igbaradi ati alaye ailewu ti 3-choro-5- (trifluoromethyl) pyridine:
Iseda:
-iwuwo: 1.578 g/ml
-Akoko farabale: 79-82 ℃
-Ojudiwọn:-52.5 ℃
-Solubility: Soluble ni Organic solvents bi ethanol, ether ati dichloromethane, die-die tiotuka ninu omi.
Lo:
-Bi reagents ati intermediates ni Organic kolaginni, lo ninu awọn kolaginni ti ipakokoropaeku, oloro ati awọn miiran Organic agbo.
-Fun iwadi ni aaye ti oogun, gẹgẹbi ninu iṣelọpọ ti awọn oogun egboogi-akàn ati awọn ami-ara.
Ọna Igbaradi:
3-chloro-5- (trifluoromethyl) pyridine le ṣe pese sile nipasẹ awọn ọna meji wọnyi:
1. Lilo pyridine bi ohun elo aise, ifasilẹ chlorination ni a ṣe ni iwaju hydrochloric acid, ati lẹhinna iṣesi trifluoromethylation ni a ṣe ni iwaju iṣuu soda trifluoromethylate.
2. Lilo 3-picolinic acid bi ohun elo aise, ifaseyin chlorination ni a ṣe ni iwaju thionyl kiloraidi, ati lẹhinna iṣesi trifluoromethylation ni a ṣe ni iwaju trifluoromethyl mercaptan.
Alaye Abo:
- 3-chloro-5- (trifluoromethyl) pyridine jẹ irritating ati pe o le fa irritation ni olubasọrọ pẹlu awọ ara ati oju. O jẹ dandan lati wọ awọn ọna aabo ti o yẹ nigba lilo, gẹgẹbi wọ awọn gilaasi aabo, awọn ibọwọ ati aṣọ aabo.
-Yẹra fun ifasimu oru rẹ ati rii daju pe a ṣe iṣẹ naa ni aaye ti o ni afẹfẹ daradara.
-Nigbati o ba wa ni ipamọ, tọju rẹ sinu apo ti a fi pa, kuro lati ina ati awọn aṣoju oxidizing.
-Nigbati o ba n sọ egbin, tọju ati sọ ọ silẹ ni ibamu pẹlu awọn ilana agbegbe.
Jọwọ ṣayẹwo Iwe Data Abo ti o yẹ (SDS) fun alaye aabo diẹ sii.
