![4-[(4-Hydroxy-2-pyrimidinyl)amino] benzonitrile (CAS# 189956-45-4) Aworan ti a ṣe afihan](https://cdn.globalso.com/xinchem/44Hydroxy2pyrimidinylaminobenzonitrile.png)
4-[(4-Hydroxy-2-pyrimidinyl) amino] benzonitrile (CAS# 189956-45-4)
4-[(4-Hydroxy-2-pyrimidinyl) amino] benzonitrile(CAS#Ọdun 189956-45-4) Alaye
| LogP | 0.9 ni pH6.6 |
| lo | 4-[(4-hydroxy-2-pyrimidinyl) amino] benzonitrile le ṣee lo bi agbedemeji ni iṣelọpọ Organic ati agbedemeji elegbogi, ati pe o le ṣee lo ninu ilana iṣelọpọ Organic yàrá yàrá ati kemikali ati iwadii oogun ati ilana idagbasoke. |
| igbaradi | ṣe iwọn 2- (methylthio) pyrimidine -4 (3H) -ọkan (3g,21mmol) ati 4-aminobenzonitrile (2.99g,25mmol) ninu ọpọn 50mL ti o wa ni isalẹ yika, ti o ni aabo nipasẹ nitrogen, laiyara kikan si 180 ℃, ati fesi fun 8 wakati. Lẹhin ti iṣeduro ti tutu, 20mL ti acetonitrile ti wa ni afikun fun itọju ultrasonic, filtration, akara oyinbo ti a fi omi ṣan pẹlu acetonitrile, ko si 4-aminobenzonitrile iyokù ti a rii nipasẹ TLC, ati ina ofeefee ti o lagbara ti a gba nipasẹ gbigbẹ akara oyinbo naa jẹ 4- (( (4-oxo -1, 6-dihydropyrimidine -2-yl) amino) benzonitrile pẹlu ikore ti 73.6%. |
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