5-Bromo-2-fluoro-4-methyl-pyridine (CAS# 864830-16-0)
| Awọn koodu ewu | R22 – Ipalara ti o ba gbe R37 / 38 - Irritating si eto atẹgun ati awọ ara. R41 - Ewu ti pataki ibaje si oju |
| Apejuwe Abo | S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun. S39 - Wọ oju / aabo oju. |
| Kíláàsì ewu | IKANU |
Ọrọ Iṣaaju
O jẹ agbo-ara Organic pẹlu agbekalẹ molikula C≡H∞BrFN, eyiti o ni atomu fluorine kan, ẹgbẹ methyl ati atom bromine kan ti o rọpo lori oruka pyridine.
Iseda:
ni a ri to, majele ti ati irritating. O jẹ tiotuka ninu awọn olomi Organic gẹgẹbi ethanol ati dimethylformamide ni iwọn otutu yara, ati pe o le ṣopọ mọ hydrogen pẹlu diẹ ninu awọn olugba mnu hydrogen (fun apẹẹrẹ, awọn ọti).
Lo:
Nigbagbogbo a lo bi ohun elo ibẹrẹ tabi agbedemeji ninu awọn aati iṣelọpọ Organic. O le ṣee lo ni igbaradi ti awọn oogun, awọn ipakokoropaeku ati awọn agbo ogun Organic miiran. Awọn ohun elo jakejado rẹ pẹlu iwadii elegbogi, iṣelọpọ kemikali ati imọ-jinlẹ ohun elo.
Ọna Igbaradi:
Ọna igbaradi ti fluorination le ṣee ṣe nipasẹ benzyl bromination ati fluorination. Ni akọkọ, agbo-ara benzyl (4-methylpyridine) ti ṣe atunṣe pẹlu benzylidene bromide lati ṣe agbejade bromobenzyl (2-bromo-4-methylpyridine). Apapọ yii lẹhinna ni ifasilẹ pẹlu hydrofluoric acid lati ṣe agbejade ọja fluorinated ti o baamu (phosphonium).
Alaye Abo:
jẹ majele, o yẹ ki o gba awọn ọna aabo ti o yẹ. Yago fun olubasọrọ pẹlu awọ ara, oju ati atẹgun atẹgun nigba isẹ. O yẹ ki o lo ni aaye ti o ni afẹfẹ daradara, ki o wọ awọn gilaasi aabo ti o yẹ, awọn ibọwọ ati awọn iboju iparada. Tọju kuro lati ina ati awọn aṣoju oxidizing, ki o yago fun iṣesi pẹlu awọn kemikali miiran. Ti o ba farahan tabi fa simu, wa imọran iṣoogun lẹsẹkẹsẹ.
