benzyl 3 6-dihydropyridine-1 (2H) -carboxylate (CAS # 66207-23-6)

Ọrọ Iṣaaju

N-CBZ-1,2,3,6-tetrahydropyridine, ti a tun mọ ni carbamate-4-hydroxybenzyl ester-1,2,3,6-tetrahydropyridine, jẹ ẹya-ara Organic. Atẹle jẹ ifihan si awọn ohun-ini rẹ, awọn lilo, awọn ọna iṣelọpọ ati alaye ailewu:

Didara:

- N-Cbz-1,2,3,6-tetrahydropyridine jẹ funfun ti o lagbara.

- O jẹ iduroṣinṣin ni iwọn otutu yara ṣugbọn decomposes ni awọn iwọn otutu giga.

- O le jẹ tiotuka ni diẹ ninu awọn olomi Organic gẹgẹbi dimethyl sulfoxide ati ethanol.

Lo:

- N-Cbz-1,2,3,6-tetrahydropyridine ni a maa n lo gẹgẹbi ẹgbẹ aabo ni iṣelọpọ Organic lati daabobo ẹgbẹ amino lori ẹgbẹ amine. O ṣe aabo fun ẹgbẹ amino lati awọn ipo aifẹ tabi awọn reagents miiran ninu iṣesi.

Ọna:

- N-Cbz-1,2,3,6-tetrahydropyridine le wa ni pese sile nipa amination ati acylation. Tetrahydropyridine ni a ṣe pẹlu carbamate nipasẹ iṣesi aminoation lati ṣe ipilẹṣẹ N-amino-1,2,3,6-tetrahydropyridine. Lẹhinna, N-amino-1,2,3,6-tetrahydropyridine ti ṣe atunṣe pẹlu chloroformate lati ṣe N-Cbz-1,2,3,6-tetrahydropyridine.

Alaye Abo:

- Awọn alaye majele ti o lopin wa fun N-Cbz-1,2,3,6-tetrahydropyridine, ṣugbọn ni gbogbogbo, o le ni irritation ati majele si eniyan.

- Yago fun olubasọrọ taara pẹlu awọ ara ati ifasimu ti eruku rẹ nigba lilo.

- Awọn iṣọra ti o yẹ, gẹgẹbi awọn ibọwọ ati ohun elo mimi, yẹ ki o mu lakoko mimu ati ibi ipamọ.

- Nigbati o ba nlo ati titoju, jọwọ tẹle awọn ilana ati awọn ilana mimu ailewu ti o yẹ.