Boc-2-Aminoisobutyric acid (CAS# 30992-29-1)

Ọrọ Iṣaaju

N-[(1,1-dimethylethoxy) carbonyl] -2-methyl-alanine, kemikali orukọ jẹ N-[(1,1-dimethylethoxy) carbonyl] -2-methylalanine, o jẹ ẹya Organic yellow. Atẹle ni apejuwe ti iseda rẹ, lilo, agbekalẹ ati alaye ailewu:

Iseda:

-Irisi: A funfun kirisita ri to.

-molikula agbekalẹ: C9H17NO4.

-Molecular iwuwo: 203.24g / mol.

-Iwọn aaye: Nipa 60-62 ° C.

-Solubility: Soluble ni Organic solvents bi ether, chloroform ati oti, insoluble ninu omi.

Lo:

N-[(1,1-dimethylethoxy) carbonyl] -2-methyl-alanine jẹ reagent ti o wọpọ ti a lo ninu iṣelọpọ Organic ati pe a lo ni akọkọ gẹgẹbi agbedemeji ni iṣelọpọ peptide. O le daabobo ẹgbẹ amino, ati pe o ni iduroṣinṣin to dara ati yiyan. Ninu idagbasoke oogun ati iṣelọpọ kemikali, N-[(1,1-dimethyllethoxy) carbonyl] -2-methyl-alanine le ṣee lo ni iṣelọpọ ti awọn polypeptides sintetiki, awọn ligands oogun, ati awọn ọja adayeba.

Ọna:

Igbaradi ti N-[(1,1-dimenthylethoxy) carbonyl] -2-methyl-alanine ni gbogbogbo nipasẹ awọn igbesẹ wọnyi:

1.2-methyl alanine ti ṣe atunṣe pẹlu dimethyl carbonate anhydride lati ṣe ina N-Boc-2-methyl alanine.

2. Idahun ti N-Boc-2-methylalanine pẹlu ọti isobutylene lati ṣe N-[(1,1-dimethyllethoxy) carbonyl] -2-methyl-alanine.

Alaye Abo:

N-[(1,1-dimenthylethoxy) carbonyl] -2-methyl-alanine jẹ ailewu diẹ labẹ awọn ipo iṣẹ deede, ṣugbọn diẹ ninu awọn iṣọra aabo ipilẹ tun nilo lati ṣe akiyesi:

-Ẹrọ aabo ti ara ẹni gẹgẹbi awọn ibọwọ lab ati awọn goggles yẹ ki o lo lakoko iṣẹ.

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