Boc-D-aspartic acid 4-benzyl ester (CAS # 51186-58-4)

Ọrọ Iṣaaju

tert-Butoxycarbonyl-D-aspartic acid 4-benzyl ester (Boc-D-aspartic acid 4-benzyl ester) jẹ agbo-ara Organic. Atẹle jẹ apejuwe ti awọn ohun-ini, awọn lilo, igbaradi ati alaye ailewu ti agbo:

Iseda:

-Irisi: White kirisita ri to

-Molecular agbekalẹ: C16H21NO6

-Molecular àdánù: 323.34g / mol

-yo ojuami: 104-106 ℃

-Solubility: Soluble ni awọn olomi-ara ti o wọpọ (bii ether, methanol, ethanol)

Lo:

-tert-Butoxycarbonyl-D-aspartic acid 4-benzyl ester jẹ lilo ni akọkọ bi reagent ninu iwadi biokemika, ti a lo lati ṣepọ tabi ṣatunṣe awọn agbo ogun Organic miiran.

- Nigbagbogbo a lo ni iṣelọpọ peptide bi ẹgbẹ aabo fun aspartic acid lati daabobo ẹgbẹ iṣẹ-ṣiṣe lori pq ẹgbẹ amino acid ati ṣe iṣesi idabobo nigbati o nilo.

Ọna Igbaradi:

Ni gbogbogbo, Boc-D-aspartic acid 4-benzyl ester ti pese sile nipasẹ iṣesi ti aspartic acid. Ni akọkọ, aspartic acid ni a ṣe pẹlu acetyl kiloraidi (AcCl) lati fun aspartic acid acetyl ester. Aspartate acetyl ester ti o ni idaabobo acetyl jẹ ifasẹyin pẹlu tert-butoxycarbonyl chloride (Boc-Cl) lati fun tert-butoxycarbonyl-D-aspartate 4-acetyl ester. Nikẹhin, tert-butoxycarbonyl-D-aspartic acid 4-benzyl ester le ṣee gba nipasẹ didasilẹ ti ọti benzyl ati ipilẹ kan.

Alaye Abo:

Boc-D-aspartic acid 4-benzyl ester ni gbogbogbo ni majele kekere, o tun jẹ dandan lati mu awọn igbese aabo ti o yẹ lakoko iṣẹ, gẹgẹbi wọ awọn ibọwọ, awọn goggles ati awọn ẹwu yàrá.

-Yago fun olubasọrọ pẹlu awọ ara ati inhalation ti eruku.

- Tọju rẹ ni ibi gbigbẹ, itura, kuro lati ina ati awọn aṣoju oxidizing.

-Nigbati mimu ati sisọnu, jọwọ tẹle awọn ilana ṣiṣe aabo ti o yẹ ati awọn ilana.