BOC-D-ASP(OBZL)-OH (CAS # 92828-64-3)

Ọrọ Iṣaaju

(3R) -4- (benzyloxy) -3- [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (orukọ ti kii ṣe ayanfẹ) ((3R) -4- (benzyloxy) -3- [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid) jẹ ẹya Organic yellow ti molikula agbekalẹ jẹ C16H21NO6.

Apapo naa jẹ itọsẹ ti aspartic acid pẹlu awọn ohun-ini wọnyi:

-Irisi jẹ funfun kirisita lulú;

-Stable ni yara otutu, sugbon yoo decompose ni ga otutu;

-Soluble ni awọn olomi Organic ti o wọpọ gẹgẹbi kẹmika, ethanol ati dichloromethane.

(3R) -4- (benzyloxy) -3- [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (orukọ ti kii ṣe ayanfẹ) ni ọpọlọpọ awọn ohun elo ni aaye oogun:

-O ti lo bi agbedemeji fun iṣelọpọ ti polypeptides ati awọn agbo ogun pẹlu awọn iṣẹku aspartic acid ninu awọn ọlọjẹ;

-O tun le ṣee lo bi agbedemeji sintetiki fun awọn oogun.

Ninu yàrá yàrá, ọna ti ngbaradi (3R) -4- (benzyloxy) -3 - [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (orukọ ti kii ṣe ayanfẹ) ni gbogbogbo nipasẹ didaṣe ẹgbẹ carboxyl ti aspartic acid pẹlu tert-butoxycarbonyl isocyanate, ati iṣafihan awọn ẹgbẹ benzyl ester nipasẹ awọn aati iṣẹ ṣiṣe ti o yẹ.

Nipa alaye ailewu, (3R) - 4- (benzyloxy) -3 - [(tert-butoxycarbonyl) amino] -4-oxobutanoic acid (orukọ ti kii ṣe ayanfẹ) ni ilodi si ati data eewu, nitorinaa iṣẹ ailewu yẹ ki o tẹle yàrá ti aṣa. ailewu itọnisọna. Wọ ohun elo aabo ti ara ẹni ti o yẹ gẹgẹbi awọn gilaasi, awọn ibọwọ ati awọn ẹwu yàrá nigba lilo tabi mimu. Ni akoko kanna, lati yago fun olubasọrọ rẹ pẹlu awọn oxidants lagbara ati awọn combustibles.