Boc-D-Glutamic acid 5-benzyl ester (CAS # 35793-73-8)
| Apejuwe Abo | S22 - Maṣe simi eruku. S24/25 - Yago fun olubasọrọ pẹlu awọ ara ati oju. |
| WGK Germany | 3 |
Ọrọ Iṣaaju
Boc-D-Glu(OBzl) -OH (Boc-D-Glu(OBzl) -OH) jẹ agbo-ara-ara kan. Atẹle ni apejuwe ti iseda rẹ, lilo, agbekalẹ ati alaye ailewu:
Iseda:
-Irisi: White kirisita lulú
-Molecular agbekalẹ: C20H25NO6
-Molecular iwuwo: 379.41
-yo ojuami: 118-120 ℃
-Solubility: Soluble ni diẹ ninu awọn olomi Organic, gẹgẹbi methanol ati dichloromethane
Lo:
- Boc-D-Glu (OBzl) -OH jẹ lilo nigbagbogbo ni aaye ti iṣelọpọ oogun ati iṣelọpọ peptide.
-O le ṣee lo bi ẹgbẹ aabo fun awọn peptides lati daabobo ẹgbẹ iṣẹ ṣiṣe hydroxyl ti glutamic acid lakoko ilana iṣelọpọ lati ṣe idiwọ awọn aati ti ko fẹ lakoko iṣesi.
Ọna Igbaradi:
- Boc-D-Glu (OBzl) -OH ni a maa n pese sile nipasẹ iṣelọpọ kemikali.
-Ni akọkọ, tert-butoxycarbonyl (Boc) ni a ṣe sinu moleku glutamic acid lati ṣe agbejade tert-butoxycarbonyl-D-glutamic acid (Boc-D-Glu).
-Lẹhinna, ẹgbẹ benzyl (Bzl) ni a ṣe sinu ẹgbẹ hydroxyl ti glutamic acid lati dagba Boc-D-Glu (OBzl) -OH (Boc-D-Glu (OBzl) -OH).
Alaye Abo:
- Boc-D-Glu(OBzl) -OH jẹ ohun elo Organic, eyiti o le fa ibinu ati ipalara si ara eniyan.
- Lakoko lilo, san ifojusi lati yago fun olubasọrọ pẹlu awọ ara, oju ati atẹgun atẹgun.
- Ninu awọn iṣẹ yàrá tabi iṣelọpọ ile-iṣẹ, ohun elo aabo ti ara ẹni yẹ ki o lo, gẹgẹbi awọn ibọwọ, awọn gilaasi aabo ati awọn iboju iparada.
- Tọju kuro lati ina ati awọn aṣoju oxidizing, tọju apo eiyan naa ki o tọju ni ibi tutu ati gbigbẹ.
Jọwọ ṣe akiyesi pe eyi jẹ alaye gbogbogbo nikan ati pe ko ṣe ibatan si awọn ipo idanwo kan pato ati awọn iṣe ailewu. Ṣaaju lilo agbo-ara yii, o gba ọ niyanju lati kan si iwe alaye aabo nkan kemikali (MSDS) ki o tẹle awọn iṣe ailewu ti o yẹ.
