BOC-D-Tyrosine methyl ester (CAS # 76757-90-9)
| WGK Germany | 3 |
Ọrọ Iṣaaju
boc-D-tyrosine methyl ester jẹ agbo-ara Organic pẹlu agbekalẹ kemikali C17H23NO5. O jẹ N-idaabobo methyl ester yellow ti D-tyrosine, ninu eyiti Boc duro fun N-tert-butoxycarbonyl (tert-butoxycarbonyl). boc-D-tyrosine ester jẹ ẹgbẹ aabo amino acid ti o wọpọ, eyiti o le daabobo nucleophile lati fesi pẹlu D-tyrosine ni iṣelọpọ.
Lilo akọkọ ti boc-D-tyrosine methyl ester jẹ bi ohun elo ibẹrẹ tabi agbedemeji ni iṣelọpọ polypeptide, ati pe a lo lati ṣajọpọ awọn polypeptides ti o ni D-tyrosine. Eyi le ṣe aṣeyọri nipa fifi ẹgbẹ N-tert-butoxycarbonyl methyl kan kun D-tyrosine.
Ọna ti ngbaradi boc-D-tyrosine methyl ester le lo ọpọlọpọ awọn ipo ifaseyin oriṣiriṣi. Ọna sintetiki ti o wọpọ ni lati fesi D-tyrosine pẹlu methanol ati sulfuric acid lati ṣe agbejade D-tyrosine methyl ester, eyiti a ṣe atunṣe pẹlu N-tert-butoxycarbonyl isocyanate lati ṣe agbejade ester boc-D-tyrosine.
Nipa alaye ailewu, boc-D-tyrosine methyl ester jẹ ailewu ni gbogbogbo labẹ awọn ipo iṣẹ ṣiṣe ti o yẹ. Sibẹsibẹ, o jẹ agbo-ara Organic ti o ni irritating ati majele. Lilo yẹ ki o tẹle awọn iṣe ailewu yàrá ti o yẹ, gẹgẹbi wọ awọn ibọwọ aabo, awọn gilaasi, ati awọn ẹwu yàrá, ati ṣiṣẹ ni agbegbe ti o ni afẹfẹ daradara. Lo ohun elo aabo kemikali ati awọn iṣakoso ẹrọ bi o ṣe pataki lati daabobo aabo ara ẹni.
