Boc-L-aspartic acid 1-benzyl ester (CAS # 30925-18-9)
| Apejuwe Abo | 24/25 - Yago fun olubasọrọ pẹlu awọ ara ati oju. |
| WGK Germany | 3 |
| HS koodu | 29242990 |
Ọrọ Iṣaaju
Boc-Asp-OBzl (Boc-Asp-OBzl) jẹ akojọpọ ti o ni awọn ohun-ini wọnyi:
1. Irisi: White crystalline ri to.
2. Ilana molikula: C24H27N3O7.
3. Iwọn molikula: 469.49g / mol.
4. Yiyọ ojuami: nipa 130-134 ° C.
Boc-Asp-OBzl jẹ lilo pupọ ni biochemistry ati kemistri Organic sintetiki, nigbagbogbo lo ninu iṣelọpọ ti awọn peptides, awọn ọlọjẹ ati awọn oogun, pẹlu awọn lilo atẹle:
1. Ṣiṣepọ Peptide: Gẹgẹbi apakan ti ẹgbẹ idabobo (ẹgbẹ idaabobo Boc), ẹgbẹ amino ninu aspartic acid amino acid le ni aabo.
2. Iwadii oogun: fun iṣelọpọ ti awọn oogun peptide pẹlu egboogi-iredodo, egboogi-tumor ati iṣẹ ilana ajẹsara.
3. Enzyme lenu: Boc-Asp-OBzl le ṣee lo fun enzymu catalyzed lenu sobusitireti.
Ọna ti ngbaradi Boc-Asp-OBzl jẹ bi atẹle:
Aspartic acid ati benzoyl kiloraidi jẹ esterified lati ṣe agbekalẹ tert-butoxycarbonyl-aspartic acid benzyl ester (Boc-Asp-OMe), eyiti o jẹ ifasẹyin pẹlu iṣuu soda hexoxide lati gba agbedemeji ni irisi N-hexanoate. Nikẹhin, o faragba iṣesi benzoylation lati ṣe agbejade Boc-Asp-OBzl.
San ifojusi si alaye aabo atẹle nigba lilo Boc-Asp-OBzl:
1. Apapọ le fa irritation ati awọn aati inira si ara eniyan, ati pe o yẹ ki o yago fun olubasọrọ taara pẹlu awọ ara ati oju.
2. Awọn igbese aabo ti ara ẹni ti o yẹ yẹ ki o mu lakoko iṣiṣẹ, gẹgẹbi wọ awọn ibọwọ ati awọn goggles.
3. Jeki gbẹ ati ki o edidi nigba ipamọ, ki o si yago fun ina ati oxidant.
4. Nigbati o ba nlo ati mimu Boc-Asp-OBzl, jọwọ tẹle awọn ilana ṣiṣe yàrá ti o tọ ati iṣẹ ailewu.
Jọwọ ṣakiyesi pe nigba lilo Boc-Asp-OBzl tabi eyikeyi awọn kemikali, o gbọdọ tẹle muna tẹle awọn ilana iṣiṣẹ ailewu ti o baamu, ati ṣe aabo ti ara ẹni ati iṣiro eewu ni ibamu si ipo gangan.
