Boc-L-Histidine (Tosyl) (CAS# 35899-43-5)

Ọrọ Iṣaaju

N (alpha) -boc-N (im) -tosyl-L-histidine (N(alpha) -boc-N (im) -tosyl-L-histidine) jẹ agbo-ara kan. Eyi ni diẹ ninu alaye nipa iseda rẹ, lilo, agbekalẹ ati ailewu:

Iseda:

-Irisi: White kirisita ri to

-Molecular agbekalẹ: C25H30N4O6S

-Molecular àdánù: 514.60g / mol

-yo ojuami: 158-161 iwọn Celsius

-Solubility: Tiotuka ni awọn ọti-lile, awọn ketones ati diẹ ninu awọn olomi Organic

Lo:

- N (alpha) -boc-N (im) -tosyl-L-histidine le ṣee lo bi ẹgbẹ idabobo lati daabobo ẹgbẹ iṣẹ-ṣiṣe histidine lakoko iṣelọpọ peptide.

-Ni kemistri peptide, o le ṣee lo bi agbo-ẹda iṣaju fun iṣelọpọ ti awọn polypeptides ti nṣiṣe lọwọ biologically.

Ọna Igbaradi:

Igbaradi ti N (alpha) -boc-N (im) -tosyl-L-histidine jẹ idiju pupọ ati pe o nilo lẹsẹsẹ awọn igbesẹ kemikali. Ọna igbaradi ti o wọpọ ni lati fesi tert-butyl chloroformate pẹlu L-histidine imidazole ester, ati lẹhinna fesi pẹlu methylbenzenesulfonyl kiloraidi lati gba ọja ibi-afẹde.

Alaye Abo:

- N (alpha) -boc-N (im) -tosyl-L-histidine le jẹ ibinu ati ifarabalẹ si awọn eniyan.

- Lakoko mimu ati ibi ipamọ, o gba ọ niyanju lati mu awọn ọna aabo ti ara ẹni ti o yẹ, gẹgẹbi wọ awọn ibọwọ, awọn goggles ati aṣọ aabo.

-Yago fun olubasọrọ pẹlu awọ ara, oju ati atẹgun atẹgun, ati ṣetọju agbegbe ile-iyẹwu ti o ni afẹfẹ daradara.

-Nigba lilo ati sisọnu agbo-ara yii, awọn ilana aabo ati awọn ilana yẹ ki o tẹle.