Boc-N-beta-Trityl-L-asparagine (CAS # 132388-68-2)

Apejuwe Abo	S22 - Maṣe simi eruku. S24/25 - Yago fun olubasọrọ pẹlu awọ ara ati oju.
WGK Germany	3
HS koodu	2924 29 70
Kíláàsì ewu	IKANU

NAA-tert-butoxycarbonyl N Γ-tryl aspartamide jẹ agbo-ara Organic, eyiti a tọka si nipasẹ abbreviation Boc-Phe-OtBu. O ni agbekalẹ C30H37NO4 ati pe o jẹ funfun ti o lagbara. Iseda:
Boc-Phe-OtBu jẹ hydrophobic ati pe ko ṣee ṣe tiotuka ninu omi, ṣugbọn ni irọrun tiotuka ninu awọn olomi Organic gẹgẹbi kẹmika, ethanol ati dichloromethane. O jẹ iduroṣinṣin si ina ati ooru.

Lo:
Boc-Phe-OtBu jẹ lilo akọkọ fun idabobo awọn ẹgbẹ ati awọn agbedemeji iṣesi ni iṣelọpọ Organic. Ninu iṣelọpọ, o le ṣee lo lati daabobo awọn amino acid aromatic, ni iṣelọpọ ti polypeptides ati awọn ọlọjẹ, aabo awọn ẹgbẹ ti nṣiṣe lọwọ lati ṣe idiwọ iṣẹlẹ ti awọn aati ẹgbẹ. Ni afikun, o tun le ṣee lo lati ṣeto awọn agbo ogun miiran, gẹgẹbi awọn oogun, awọn awọ ati awọn ohun elo Organic.

Ọna Igbaradi:
Igbaradi ti Boc-Phe-OtBu jẹ aṣeyọri nipataki nipasẹ iṣesi kemikali. Ọna ti o wọpọ ni lati fesi p-benzoic acid pẹlu t-butyl hydroxyformate lati ṣe agbejade p-tert-butoxycarbonyl benzoate. Lẹhinna o ṣe atunṣe pẹlu triphenylamine lati fun ọja ikẹhin Boc-Phe-OtBu.

Alaye Abo:
Boc-Phe-OtBu jẹ ailewu labe lilo deede. Sibẹsibẹ, gẹgẹbi kemikali, o tun nilo lati wa ni ipamọ ati mu daradara. Yago fun olubasọrọ pẹlu awọn oxidants to lagbara, dena ifasimu ti eruku ati yago fun olubasọrọ ara. Lakoko lilo, wọ ohun elo aabo ti ara ẹni ti o yẹ, gẹgẹbi awọn ibọwọ ati awọn gilaasi aabo. Ni iṣẹlẹ ti olubasọrọ lairotẹlẹ tabi jijẹ, wa imọran iṣoogun lẹsẹkẹsẹ ki o pese alaye si dokita nipa kemikali. Awọn ofin ati ilana aabo agbegbe yẹ ki o tẹle nigba mimu ati sisọnu egbin.