CBZ-D-ALLO-ILE-OH (CAS# 55723-45-0)

Ọrọ Iṣaaju

ZD-allo-Ile-OH . DCHA (ZD-allo-Ile-OH · DCHA) jẹ agbo-ara Organic ati reagent fun idabobo awọn amino acids. Atẹle ni apejuwe ti iseda rẹ, lilo, agbekalẹ ati alaye ailewu:

Iseda:

-Kẹmika agbekalẹ: C23H31NO5

-Molecular iwuwo: 405.50g / mol

-Irisi: White kirisita ri to

-Iwọn ojuami: 105-108 ° C

-Solubility: Soluble ni Organic epo bi acetone, ether, dichloromethane, insoluble ninu omi.

Lo:

- ZD-allo-Ile-OH . DCHA jẹ reagent ti a lo lati daabobo awọn amino acids. Nipa iṣafihan ẹgbẹ Cbz kan lori ẹgbẹ amino ti amino acid kan, iyipada lairotẹlẹ ti ẹgbẹ amino ninu iṣesi iṣelọpọ kemikali le ṣe idiwọ.

- Nigbagbogbo a lo ni iṣelọpọ peptide, paapaa fun iṣelọpọ ti awọn ilana peptide pẹlu awọn ẹya pataki tabi awọn iṣẹ ṣiṣe.

Ọna Igbaradi:

- ZD-allo-Ile-OH. Igbaradi ti DCHA nigbagbogbo bẹrẹ lati D-isoleucine, ati lẹhinna fesi pẹlu Cbz anhydride fun esterification lati ṣafihan ẹgbẹ aabo Cbz. Nikẹhin, DCHA (dichloroformic acid) ni a ṣe pẹlu amino acid lati ṣe iyọ ti o baamu.

Alaye Abo:

- ZD-allo-Ile-OH . DCHA ko ni majele ti, ṣugbọn o yẹ ki o ṣe itọju pẹlu iṣọra. Yago fun olubasọrọ pẹlu awọ ara ati oju, wọ awọn ibọwọ aabo ati awọn gilaasi ti o ba jẹ dandan.

- Lakoko lilo, awọn ilana iṣiṣẹ yàrá boṣewa yẹ ki o tẹle ati pe o yẹ ki o lo ohun elo eefun ti o yẹ.

-Nigbati o ba wa ni ipamọ, tọju agbo naa ni gbigbẹ, aaye tutu kuro lati awọn orisun ti ina ati ina.