FMOC-Glycine (CAS# 29022-11-5)
| Awọn aami ewu | Xi - Irritant |
| Awọn koodu ewu | 36/37/38 - Irritating si oju, eto atẹgun ati awọ ara. |
| Apejuwe Abo | S24/25 - Yago fun olubasọrọ pẹlu awọ ara ati oju. S36 - Wọ aṣọ aabo to dara. S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun. |
| WGK Germany | 3 |
| HS koodu | 29242995 |
Ọrọ Iṣaaju
N-Fmoc-glycine jẹ itọsẹ amino acid pataki, ati orukọ kemikali rẹ jẹ N- (9H-fluoroeidone-2-oxo) -glycine. Atẹle jẹ ifihan si awọn ohun-ini, awọn lilo, awọn ọna igbaradi ati alaye ailewu ti N-Fmoc-glycine:
Didara:
- Irisi: Funfun tabi pa-funfun ri to
- Solubility: Soluble ni Organic solvents bi dimethyl sulfoxide (DMSO) ati methylene kiloraidi, die-die tiotuka ninu oti, fere insoluble ninu omi.
Lo:
N-Fmoc-glycine jẹ lilo akọkọ fun iṣelọpọ peptide ni iṣelọpọ-alakoso ti o lagbara (SPPS). Gẹgẹbi amino acid ti o ni aabo, o ti wa ni afikun si pq polypeptide nipasẹ iṣelọpọ-ipele ti o lagbara, ati nikẹhin peptide ibi-afẹde ni a gba nipasẹ iṣesi ti awọn ẹgbẹ idabobo.
Ọna:
Igbaradi ti N-Fmoc-glycine jẹ igbagbogbo nipasẹ awọn aati kemikali. Glycine ti ṣe atunṣe pẹlu ọti N-fluorophenyl methyl ati ipilẹ kan (fun apẹẹrẹ, triethylamine) lati ṣe agbejade N-fluorophenylmethyl-glycine hydrochloride. Lẹhinna, hydrochloric acid ti yọ kuro nipasẹ diẹ ninu iru deacidifier, gẹgẹbi dimethyl sulfoxide tabi sec-butanol, lati fun N-Fmoc-glycine.
Alaye Abo:
N-Fmoc-Glycine jẹ ailewu jo labẹ awọn ipo iṣẹ deede
- Jọwọ wọ awọn ohun elo aabo ti ara ẹni ti o yẹ gẹgẹbi awọn ibọwọ lab ati aabo oju.
- Yago fun ifasimu tabi olubasọrọ pẹlu awọ ara ati oju.
- Tẹle gbogbo awọn ilana aabo ti o yẹ ati awọn ilana yàrá nigba titoju ati mimu.
- San ifojusi si ikojọpọ ti ina ati ina aimi lakoko ilana mimu lati ṣe idiwọ eewu ti ina ati bugbamu.
- Idoti ti o tọ ni ibamu pẹlu ibi ipamọ ati awọn ibeere isọnu ti nkan naa.
