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Levodopa (CAS # 59-92-7) Aworan Afihan
  • Levodopa (CAS# 59-92-7) 1

Levodopa (CAS# 59-92-7)

Ohun-ini Kemikali:

Fọọmu Molecular C9H11NO4
Molar Mass 197.19
iwuwo 1.3075 (iṣiro ti o ni inira)
Ojuami Iyo 276-278 °C (tan.)
Ojuami Boling 334.28°C (iṣiro ti o ni inira)
Yiyi pato (α) -11.7º (c=5.3, HCl 1N)
Oju filaṣi 225°C
Omi Solubility Die-die tiotuka ninu omi, dilute hydrochloric acid ati formic acid. Ailopin ninu ethanol.
Solubility Ni irọrun tiotuka ni dilute hydrochloric acid ati formic acid, tiotuka ninu omi, ti ko ṣee ṣe ninu ethanol, benzene, chloroform ati ethyl acetate
Vapor Presure 7.97E-09mmHg ni 25°C
Ifarahan Funfun si wara funfun kristali lulú
Àwọ̀ Funfun si ọra-wara
Merck 14.5464
BRN 2215169
pKa 2.32 (ni 25℃)
Ibi ipamọ Ipo 2-8°C
Iduroṣinṣin Idurosinsin. Ibamu pẹlu awọn aṣoju oxidizing lagbara. Ina ati air kókó.
Ni imọlara Ifarabalẹ si ina ati afẹfẹ
Atọka Refractive -12 ° (C=5, 1mol/LH
MDL MFCD00002598
Ti ara ati Kemikali Properties yo ojuami 295 ° C
Yiyi opitika kan pato -11.7 ° (c = 5.3, 1N HCl)
Lo Oogun ti o munadoko fun itọju paralysis ti mọnamọna, ti a lo ni akọkọ fun Arun Pakinsini, ati bẹbẹ lọ

Alaye ọja

ọja Tags

Awọn aami ewu Xn – ipalara
Awọn koodu ewu R22 – Ipalara ti o ba gbe
R36 / 37/38 - Irritating si oju, eto atẹgun ati awọ ara.
R20 / 21/22 - ipalara nipasẹ ifasimu, ni olubasọrọ pẹlu awọ ara ati ti o ba gbe.
Apejuwe Abo S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun.
S36 - Wọ aṣọ aabo to dara.
S24/25 - Yago fun olubasọrọ pẹlu awọ ara ati oju.
WGK Germany 3
RTECS AY5600000
FLUKA BRAND F koodu 10-23
TSCA Bẹẹni
HS koodu 29225090
Oloro LD50 ninu awọn eku (mg / kg): 3650 ± 327 orally, 1140 ± 66 ip, 450 ± 42 iv,> 400 sc; ninu akọ, abo eku (mg/kg):>3000,>3000 ẹnu; 624, 663 ip; > 1500,> 1500 sc (Clark)

 

Ọrọ Iṣaaju

Awọn ipa elegbogi: awọn oogun paralysis anti-tremor. O wọ inu iṣan ọpọlọ nipasẹ idena-ọpọlọ ẹjẹ, ati pe o jẹ decarboxylated nipasẹ dopa decarboxylase ati iyipada sinu dopamine, eyiti o ṣe ipa kan. A lo fun paralysis akọkọ tremor ati ailera paralysis paralysis ti kii ṣe ti oogun. O ni ipa to dara lori iwọntunwọnsi ati ìwọnba, àìdá tabi talaka agbalagba.

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