N-Boc-N'-(2-chlorobenzyloxycarbonyl)-L-lysine (CAS# 54613-99-9)
| Awọn aami ewu | Xi - Irritant |
| Awọn koodu ewu | 36/37/38 - Irritating si oju, eto atẹgun ati awọ ara. |
| Apejuwe Abo | S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun. S36 - Wọ aṣọ aabo to dara. S24/25 - Yago fun olubasọrọ pẹlu awọ ara ati oju. |
| WGK Germany | 3 |
| HS koodu | 29242990 |
Ọrọ Iṣaaju
N-tert-butoxycarbonyl-N'-(2-chlorobenzyloxycarbonyl) -L-lysine jẹ ẹya ara-ara agbo, ti a tọka si bi CBZ-L-lysine. Atẹle ni iseda, lilo, ọna igbaradi ati alaye ailewu ti agbo:
Didara:
CBZ-L-lysine jẹ kristali ti ko ni awọ ti o lagbara pẹlu õrùn kan pato. O ni solubility ti o dara ati pe o jẹ tiotuka ninu awọn ohun elo ti o wọpọ gẹgẹbi methanol, chloroform, ati dimethyl sulfoxide.
Lo:
CBZ-L-lysine ni a maa n lo bi ọkan ninu awọn ẹgbẹ aabo amino ni iṣelọpọ Organic lati daabobo awọn ẹgbẹ iṣẹ ṣiṣe amino ti o ni itara si agbegbe. Ninu iṣelọpọ ti awọn agbo ogun peptide, CBZ-L-lysine le ṣee lo lati daabobo ẹgbẹ amino ti lysine lati le daabobo tabi ṣakoso ifasilẹ rẹ ni awọn aati pato.
Ọna:
Igbaradi ti CBZ-L-lysine ni a maa n ṣe nipasẹ awọn igbesẹ wọnyi: L-lysine ti ṣe atunṣe pẹlu erogba oloro lati gba carbonate ti o baamu; Lẹhinna, carbonate ti ṣe atunṣe pẹlu tert-butoxycarbonyl magnẹsia kiloraidi lati gba lysine idaabobo acetyl; Lẹhinna o ṣe atunṣe pẹlu 2-chlorobenzyl iodine kiloraidi ati alkali lati gba CBZ-L-lysine.
Alaye Abo:
Lilo CBZ-L-lysine yẹ ki o wa pẹlu awọn iṣọra ailewu atẹle: o le jẹ irritating si awọn oju, awọ ara ati atẹgun atẹgun, ati pe o yẹ ki o yago fun olubasọrọ taara lakoko iṣẹ. Awọn ohun elo aabo ti o yẹ gẹgẹbi awọn gilaasi aabo kemikali ati awọn ibọwọ yẹ ki o wọ lakoko lilo. O yẹ ki o ṣiṣẹ ni agbegbe ti o ni afẹfẹ daradara lati yago fun fifun ifasimu lati inu agbo. Ti ijamba ba waye, agbegbe ti o kan yẹ ki o fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ati iranlọwọ iṣoogun yẹ ki o wa.
