N-Boc-N'-trityl-L-glutamine (CAS # 132388-69-3)

WGK Germany	3
HS koodu	29242990

N-Boc-N '-trityl-L-glutamine (N-Boc-N'-trityl-L-glutamine, abbreviated bi Boc-Gln (Trt) -OH) jẹ ẹya Organic yellow. O ni awọn ohun-ini wọnyi: 1. Irisi: funfun kirisita lulú.
2. molikula agbekalẹ: C39H35N3O6
3. Molikula iwuwo: 641.71g / mol
4. Oju ipadanu: 148-151 ° C
5. Solubility: Soluble ni ọpọlọpọ awọn olutọpa ti ara, gẹgẹbi dimethyl sulfoxide (DMSO) ati dichloromethane.
6. Iduroṣinṣin: jo idurosinsin labẹ mora esiperimenta ipo.

Ninu iṣelọpọ kemikali, N-Boc-N '-tryl-L-glutamine ni igbagbogbo lo bi ẹgbẹ aabo amino acid tabi agbedemeji. Awọn lilo akọkọ rẹ pẹlu:

1. ti a lo bi ẹgbẹ idaabobo glutamine ni peptide ati iṣelọpọ amuaradagba.
2. Ninu iwadi ti awọn oogun sintetiki, a lo lati ṣajọpọ awọn analogs glutamine.
3. ti a lo bi agbedemeji lati ṣajọpọ awọn agbo ogun Organic miiran.

Ọna fun igbaradi N-Boc-N '-tryl-L-glutamine ni gbogbogbo bi atẹle:

1. Ni akọkọ, fesi N-idaabobo glutamine (gẹgẹbi N-Boc-L-glutamine) pẹlu trityl halide (gẹgẹbi trityl chloride) lati gba N-Boc-N '-trityl-L-glutamine.

Alaye Abo:
N-Boc-N '-trityl-L-glutamine, gẹgẹbi agbo-ara Organic, jẹ ailewu labe lilo ati ibi ipamọ to pe. Sibẹsibẹ, awọn ọran wọnyi tun nilo lati ṣe akiyesi:

1. Yẹra fun olubasọrọ pẹlu oju, awọ ara ati atẹgun atẹgun. Lo awọn ibọwọ aabo kemikali ati awọn goggles.
2. Fipamọ ni ibi gbigbẹ, itura.
3. Ni ibamu pẹlu awọn ilana ailewu ati mu daradara ati sọsọ egbin ti agbo-ara naa.