N-Cbz-L-Aspartic acid 4-benzyl ester (CAS# 3479-47-8)
| Awọn koodu ewu | 50 – Majele pupọ si awọn oganisimu omi |
| Apejuwe Abo | 61 – Yago fun itusilẹ si ayika. Tọkasi awọn ilana pataki / awọn iwe data aabo. |
| UN ID | 3077 |
| WGK Germany | 3 |
| HS koodu | 29242990 |
Ọrọ Iṣaaju
N-benzyloxycarbonyl-L-aspartate 4-benzylester, ti a tun mọ ni Boc-L-phenylalanine benzyl ester, jẹ agbo-ara Organic. Eyi ni diẹ ninu alaye nipa awọn ohun-ini rẹ, awọn lilo, awọn ọna iṣelọpọ, ati ailewu:
Didara:
N-benzyloxycarbonyl-L-aspartate 4-benzyl ester jẹ kristali funfun ti o lagbara ti o jẹ tiotuka ni diẹ ninu awọn olomi Organic gẹgẹbi kẹmika, awọn ethers, ati awọn olomi ester.
Nlo: O le ṣee lo bi ohun elo aise fun iṣelọpọ ti awọn agbo ogun heterocyclic gẹgẹbi furan, indole ati pyrrole, ati pe o le ṣee lo fun iṣelọpọ ati iyapa awọn agbo ogun chiral.
Ọna:
Igbaradi ti N-benzyloxycarbonyl-L-aspartic acid 4-benzyl ester ni gbogbogbo nipasẹ didaṣe L-phenylalanine pẹlu urea lati ṣe agbekalẹ N-benzyloxycarbonyl-L-aspartic acid, ati lẹhinna fesi pẹlu ọti benzyl lati dagba ọja ikẹhin. Ilana iṣelọpọ ni gbogbogbo ni a ṣe labẹ aabo ti awọn gaasi inert (bii nitrogen), ati pe o nilo imọ-ẹrọ iṣelọpọ kan ati iriri iṣẹ ṣiṣe adanwo.
Alaye Abo:
N-benzyloxycarbonyl-L-aspartate 4-benzyl ester ko ni eewu aabo kan pato labẹ awọn ipo lilo deede, ṣugbọn atẹle yẹ ki o tun ṣe akiyesi:1. Yago fun olubasọrọ taara pẹlu awọ ara ati oju lati yago fun ibinu. 2. Awọn ipo atẹgun ti o dara yẹ ki o wa ni itọju nigba lilo. 3. Nigbati o ba tọju, o yẹ ki o wa ni ipamọ ni dudu, gbigbẹ ati iwọn otutu kekere. 4. Ti o ba fa simu tabi ti mu, wa itọju ilera lẹsẹkẹsẹ. Nigbati o ba n mu ati lilo awọn kemikali, awọn ilana ṣiṣe aabo ti o yẹ ati awọn ọna aabo ti ara ẹni yẹ ki o wa ni ifaramọ ni muna lati rii daju lilo ailewu.
