N-Cbz-L-Leucine (CAS# 2018-66-8)
Ewu ati Aabo
| Awọn aami ewu | Xn – ipalara |
| Awọn koodu ewu | R10 - flammable R20/22 - ipalara nipasẹ ifasimu ati ti o ba gbe. R37 / 38 - Irritating si eto atẹgun ati awọ ara. R40 - Ẹri to lopin ti ipa carcinogenic R41 - Ewu ti pataki ibaje si oju R36 / 37/38 - Irritating si oju, eto atẹgun ati awọ ara. R20 / 21/22 - ipalara nipasẹ ifasimu, ni olubasọrọ pẹlu awọ ara ati ti o ba gbe. R67 – Vapors le fa drowsiness ati dizziness R63 – Owun to le ewu ipalara si awọn unborn ọmọ R19 - Le dagba awọn ibẹjadi peroxides |
| Apejuwe Abo | S16 – Jeki kuro lati awọn orisun ti iginisonu. S26 - Ni ọran ti olubasọrọ pẹlu awọn oju, fi omi ṣan lẹsẹkẹsẹ pẹlu ọpọlọpọ omi ki o wa imọran iṣoogun. S36 / 37/39 - Wọ aṣọ aabo to dara, awọn ibọwọ ati aabo oju / oju. S45 – Ni ọran ti ijamba tabi ti o ba ni ailara, wa imọran iṣoogun lẹsẹkẹsẹ (fi aami han nigbakugba ti o ṣee ṣe.) S36 - Wọ aṣọ aabo to dara. S36 / 37 - Wọ aṣọ aabo ati awọn ibọwọ to dara. S60 – Ohun elo yii ati ohun elo rẹ gbọdọ jẹ sọnu bi egbin eewu. |
| UN ID | UN 1993 3/PG 3 |
| WGK Germany | 3 |
| RTECS | OH2921000 |
| HS koodu | 29242990 |
N-Cbz-L-Leucine (CAS# 2018-66-8) ifihan
Cbz-L-leucine, orukọ kikun ti Boc-L-leucine (Boc duro fun ẹgbẹ idabobo dibutoxycarbonyl), jẹ itọsẹ amino acid kan. Atẹle jẹ ifihan si iseda rẹ, lilo, awọn ọna iṣelọpọ ati alaye ailewu:
Didara:
- Irisi: White kirisita ri to
- Soluble: Tiotuka ni ethanol, dimethylformamide (DMF) ati dichloromethane
Lo:
- CBZ-L-Leucine jẹ ẹgbẹ aabo amino acid ti o wọpọ ti o ṣe aabo fun ẹgbẹ hydroxyl ti leucine lakoko iṣelọpọ ti awọn peptides lati ṣe idiwọ lati fesi pẹlu awọn ifaseyin miiran. Ni iṣelọpọ peptide nibiti ọpọlọpọ awọn iṣẹku leucine nilo lati ṣafihan, Cbz-L-leucine le ṣee lo lati daabobo ẹgbẹ hydroxyl ti leucine fun awọn ilana iṣelọpọ atẹle.
Leucine jẹ amino acid pataki ti o ṣe ipa pataki ninu eto amuaradagba ati iṣẹ.
Ọna:
- Igbaradi ti Cbz-L-leucine ni gbogbo igba ti a gba nipasẹ iṣesi ti leucine pẹlu Boc-OSu (Boc-N-nitrocarbonyl-L-leucine). Ninu ifarabalẹ, Boc-OSu n ṣiṣẹ bi olupilẹṣẹ ti ẹgbẹ aabo ati pe o ni ifarabalẹ esterification pẹlu leucine lati ṣe ipilẹṣẹ Cbz-L-leucine.
Alaye Abo:
- Cbz-L-leucine jẹ kemikali ati pe o yẹ ki o wa ni ipamọ daradara kuro ni ina ati awọn oxidants.
- Lakoko lilo, yago fun simi eruku rẹ tabi wiwa sinu olubasọrọ pẹlu awọ ara ati oju.
Tẹle awọn iṣe ailewu ti o yẹ nigba mimu ati titọju, ati wọ ohun elo aabo ti ara ẹni ti o yẹ gẹgẹbi awọn ibọwọ lab ati aabo oju.
