N-tert-Butoxacarbonyl-O-benzyl-L-threonine (CAS# 15260-10-3)

Ọrọ Iṣaaju
N-Boc-O-benzyl-L-threonine jẹ ẹya Organic yellow. Atẹle jẹ ifihan si iseda rẹ, lilo, ọna iṣelọpọ ati alaye ailewu:

Didara:
N-Boc-O-benzyl-L-threonine jẹ funfun tabi parẹ-funfun kirisita ti o lagbara, tiotuka ninu awọn nkanmimu Organic ti o wọpọ gẹgẹbi ethanol, dimethylformamide, chloroform, ati bẹbẹ lọ.

Lo:
N-Boc-O-benzyl-L-threonine jẹ agbedemeji pataki ni iṣelọpọ Organic ati pe a lo nigbagbogbo ni iṣelọpọ ti awọn peptides ati awọn ọlọjẹ. O le ṣee lo bi ẹgbẹ aabo ni ila-aabo, kolupọ omi ati iṣọpọ-iṣan lati yago fun yiyan ẹgbẹ ninu ilana iṣe, lati le mu yiyan ẹgbẹ kun ati ikore ti ifura.

Ọna:
Igbaradi ti N-Boc-O-benzyl-L-threonine ni a ṣe nipasẹ iṣelọpọ kemikali. Threonine ti wa ni acylated pẹlu N-tert-butoxycarbonyl (Boc-O-benzyl) ati awọn activators bi N, N-diisopropylethylamine (DIPEA) tabi carbodiimide (DCC) ti wa ni afikun. Lẹhin iṣesi, N-Boc-O-benzyl-L-threonine ti gba.

Alaye Abo:
N-Boc-O-benzyl-L-threonine ni profaili aabo to gaju, ṣugbọn bi ohun elo Organic, awọn iṣọra aabo atẹle yẹ ki o tun ṣe akiyesi: yago fun olubasọrọ pẹlu awọ ara, oju ati eto atẹgun; Wọ awọn ibọwọ aabo, awọn goggles, ati awọn iboju iparada nigbati o nṣiṣẹ; Ṣiṣẹ ninu yàrá ti o ni afẹfẹ daradara; Yago fun olubasọrọ pẹlu oxidants ati acids nigba ti o ti fipamọ. Ti o ba ti fi ọwọ kan lairotẹlẹ tabi fa simu, o yẹ ki o fo tabi ṣe itọju pẹlu itọju ilera ni akoko.