tert-butyl 2 4-dioxopiperidine-1-carboxylate (CAS# 845267-78-9)

Fọọmu Molecular	C10H15NO4
Molar Mass	213.23
iwuwo	1.199
Ojuami Boling	373.8± 35.0 °C (Asọtẹlẹ)
Oju filaṣi	179.9°C
Vapor Presure	8.72E-06mmHg ni 25°C
pKa	10.67± 0.20 (Asọtẹlẹ)
Ibi ipamọ Ipo	Tọju ni aaye dudu, Ti di ni gbigbẹ, Iwọn otutu yara
Atọka Refractive	1.493
MDL	MFCD10566071

Alaye ọja

Awọn koodu ewu	20/21/22 - Ipalara nipasẹ ifasimu, ni olubasọrọ pẹlu awọ ara ati ti o ba gbe mì.
Apejuwe Abo	S23 – Maṣe simi oru. S24/25 - Yago fun olubasọrọ pẹlu awọ ara ati oju.
WGK Germany	3
HS koodu	29337900

Lo	2, 4-dipiperidon-1-formate tert-butyl formate jẹ iṣelọpọ ti awọn itọsẹ phenoxymethyl-dihydrothiazolopyridone Reactants ninu ọja naa, gẹgẹbi oluyipada igbekalẹ rere yiyan (PAM) ti iṣelọpọ metabolized glutamate 5 (mGlu5).
ohun elo	2, 4-dioperidone-1-tert-butyl formate jẹ lilo akọkọ bi agbedemeji Organic ati agbedemeji elegbogi, ati pe o le ṣee lo ninu iwadii yàrá ati ilana idagbasoke ati ilana iṣelọpọ oogun kemikali.
igbaradi	igbese a: fi EDCI (191.7g) si DMF (400mL) ojutu ti 3- (tert-butoxycarbonylamino) propionic acid (189.2g,1.0mol), meldamic acid (144.1g,1.0mol) ati DMAP (135.0g,1.1mol) ) tutu nipasẹ yinyin iwẹ, 1.0mol). Abajade reactants won rú moju ni yara otutu. Idahun naa ti pa pẹlu 200mL H2O. Abajade adalu ti a fi kun dropwise to H2O (2.0L) labẹ darí saropo. Ohun elo ti o gba ni a ti wẹ ati ki o fọ daradara pẹlu omi si pH 7 lati gba ọja naa (283g, 90% ikore). Igbesẹ B: Ojutu ti 3- (2, 2-dimethyl-4, 6-dioxo-1, 3-dioxan-5-yl) -3-oxopropylcarbamate tert-butyl ester (100g,317.46mmol) ni toluene (1500mL) ti wa ni kikan ni 100 ° C fun wakati 4. Awọn reactants ti wa ni tutu si iwọn otutu yara ati idojukọ labẹ titẹ idinku lati gba ọja robi kan. Ọja naa (56g,83% ikore) jẹ mimọ nipasẹ lilọ-MTBE.